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Narrative Essay

July 2, 2025/in Nursing Questions /by Besttutor

Write a 500 words personal narrative Essay, describing what you hope to gain from your college experience.You may include details about what you have learn in college and what you hope to learn in college that will help you to achieve your career goals.

Please note: the goal of narration is to tell a story. for this assignment Im asking you to narrate your story of your college experience once you have graduated.

NOTE: does not have to be too formal, my career is Bachelor in Nursing

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Concept Synthesis Paper on Personal Nursing Philosophy

July 2, 2025/in Nursing Questions /by Besttutor

Instructions

Concept Synthesis Paper on Personal Nursing Philosophy

You are required to submit a scholarly paper in which you will identify, describe, research, and apply the concepts that underlie your personal philosophy for professional nursing practice.

This will help you identify your own values and beliefs about the established metaparadigms and metatheories of the discipline. It will also help you identify and articulate concepts relevant to your specific practice. This paper is intended to be an exercise in clarification and organization of your professional foundation. You are also required to provide a list of assumptions from personal nursing practice that illustrate the concepts and framework of your theory.

Your paper should follow a format that includes:

  • Nursing Autobiography: A brief (1 page) discussion of your background in nursing.
  • The Four Metaparadigms: Identification, discussion, and documentation from the literature of your perspective on the basic four metaparadigms/concepts of patient, nurse, health, and environment.
  • Two Practice-Specific Concepts: Identification, discussion, and documentation from the literature of your perspective on at least two other concepts specific to your own practice.
  • List of Propositions: A numbered list of at least five propositions or assumption statements that clearly connect the concepts described.

Each week, you will complete various segments of your Concept Synthesis Paper and submit it to the Submissions Area for facilitator feedback when necessary. Your paper should integrate these discrete elements and reflect your personal nursing philosophy.

Your Concept Synthesis Paper on your Personal Nursing Philosophy is due in Week 3. However, it is recommended that you begin working on your paper from Week 1 onwards and complete the various components related to the paper week wise as you progress through the course. The suggested tasks for each week are:

Week 1: Nursing Biography and The Four Metaparadigms of Nursing
Week 2: Two Practice-specific Concepts, and List of Propositions/Assumptions
Week 3: Due: Concept Synthesis Paper on Personal Nursing Philosophy

Consider the following questions as you complete your various tasks related to this assignment.

1.

How do I define and employ the four basic metaparadigms of nursing theory in my professional practice?

2.

What are the major concepts I employ that are unique to my professional practice?

3.

What philosophies and theories from the literature of nursing and other disciplines/domains are consistent with these concepts?

4.

How are the concepts of transcultural nursing, the health promotion model, skill acquisition, role theory, and change theory specifically integrated into  my philosophy and practice?

5.

What research supports these theories and concepts?

6.

How do I integrate role and change theory into my professional practice and how may these theories be applied to the organization in which I practice?

The paper is to be thoroughly researched and well documented, with relevant material from the nursing theorists presented incorporated into the paper. Use the current edition of the APA Manual throughout the paper. Sources should focus on references from nursing theory but may also include conceptual and theoretical material from other professional domains. The paper, excluding references or appendices, is to be limited to 6-10 pages. Writing should be succinct and well organized, as it is impossible for the facilitator to evaluate form and content separately.

Your philosophy/framework is to be given a title that is appropriate to its content and emphasis.

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DB3

July 2, 2025/in Nursing Questions /by Besttutor

How does the nurse manager or leader play a role in reengineering of the health care? 1 page.

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Simple Assignment

July 2, 2025/in Nursing Questions /by Besttutor

The following case studies are provided to give you experience in completing risk assessments.  These studies allow you to identify the process that one goes through in risk assessments.  (This implies, “This is what the case study tells me, this is what I need to know, this is what I would do with the information once it is determined…Perhaps you should start out saying, “The first step I took…)  The whole point of this process is to get you familiar with the components of the risk assessment process and to give you practice with trying to find the different components and then put them together to make conclusions. My approach to this assignment is to act like a detective.  Ask questions of yourself, discuss where the questions lead you, what more questions are revealed once you have gathered the initial data, etc.

The final research project has you actually doing the process for a particular toxicant with you researching for the information you need.

FIRST THING:  Also, though more important for stage 2, you will need to determine why you are doing the risk assessment.   SPECIFICALLY WRITE OUT YOUR PURPOSE FIRST THING.  In an accident case it might be to determine what the long-term health effects will be to those who were exposed but survived.  It might be to determine how high the risks of exposure are to nearby residents, or if exposure were to happen, what the risks to them might be.  In a workplace case the risk assessment might be to determine to what level the clean-up (of air, water, etc.) should be to protect human health.  It might be to determine if any workplace accommodations need to be made.  In a medically related case the risk assessment might be to characterize the risks to workers associated with a medically related accident or incident.  Its purpose might be to determine the risks to the general public from an incident.  If you narrow down your focus it will make how you go about dose response investigation and exposure assessment more straightforward.

You may NOT use any of these case studies for your research project.

Staged Project (Case Study 1), Stage 1: Define the purpose of the Risk Assessment.  Apply the steps of hazard identification to identify the hazard in each case study. Be sure to discuss the evidence that led you to your decision about the identification of the hazard. If the case study doesn’t provide the evidence then discuss how you would go about getting the evidence you need and what source would you use.  Discuss how the evidence supports your conclusion about the identification of the hazard.  Keep in mind the information you need for toxickinetics and toxicodynamics.

Staged Project (Case Study 2), Stage 2: Exposure assessment, dose-response assessment and risk characterization. Based on the case studies above and the hazard identified, discuss how you would approach an exposure assessment, a dose-response assessment and a final risk characterization.

NOTE: not all of these case studies are real incidences.  You have been given choices so that you may explore areas within your interests.

Choose ONE study from EACH AREA below (this means you will comment on THREE case studies – one from community-based, one from work-based and one from medically based.

Community-Based Hazard Exposure:

Choose one (1) of these –

A. http://www.ops.fhwa.dot.gov/publications/fhwahop08014/case4_0.htm

Graniteville, S. Carolina Case study, Chlorine

Note that this case study either tells you, or strongly hints at what the hazard is.  Ignore this, and tell me what logic you used to determine what the hazard actually was.

B. http://www.mhhe.com/Enviro-Sci/CaseStudyLibrary/Topic-Based/CaseStudy_LoveCanal.pdf

New York Case Study, water and ground pollution

Workplace-Based Hazard Exposure:

Choose one (1) of these –

A:  An employee developed occupational asthma after working for a large multi-national company in Gloucester. He was employed between 1995 and 2004 as a solderer and was exposed to rosin based (colophony) solder fume during his career.  The company had no fume extraction equipment to remove rosin based fumes from the workroom air or from the breathing zones of its solderers.

His health was deteriorating from 1999 onwards and he was taking time off work due to breathing difficulties.

B:  Jenkins Chemical

Background

Jenkins Chemicals is a small/medium size specialist chemical manufacturing

company based in Hartfordshire, England. The company supplies Hydrazine Hydrate (a known carcinogen) for use as an oxygen scavenger of boiler feed water, preventing corrosion damage in high pressure boilers used in the power generating industries and used as a chemical intermediate for a number of different applications. Under the Chemicals (Hazard Information and Packaging for Supply) Regulations, Hydrazine Hydrate is a Category 2 carcinogen – believed to cause cancer in humans. Whilst under the EU Classification Labeling and Packaging regulations it will carry a category 1B (H350) Carcinogen classification.

The Problem

The company originally used a manual operation to decant the Hydrazine Hydrate

into storage tanks using a hose and lance system. A similar approach was used to

prepare Hydrazine Hydrate for supply to customers; manual decanting into

containers of various sizes up to 1 tonne bulk containers. When HSE inspected the site and assessed both processes, HSE and the company agreed that there was a heavy reliance on both personal protective equipment (PPE) and Respiratory Protective equipment (RPE). The company also had a local exhaust

ventilation system on site which would only remove escaping vapors when near the

source of exposure, therefore offering a limited level of protection. This was important

given that the company had discovered that airborne exposure concentrations during

manual transfers were in excess of the assigned regulatory exposure limit for

Hydrazine, although no employee was known to be exposed to hydrazine vapor

above the regulatory limits.

Substitution – using a less harmful chemical with similar properties was not a viable

option for the company as there was no other practicable alternative oxygen

scavenger for use in high pressure boilers. Overall, the potential for worker exposure coupled with a heavy reliance on PPE raised concerns for both HSE and the company.

At the heart of the shared dilemma was the need to minimize the potential for worker

exposure to a vital, but harmful chemical.

C.  Case Study: Jennifer*

Jennifer is a nulliparous, 30-year-old healthy woman who presents to your office for her annual well-woman exam. She was recently married and is contemplating pregnancy within the next year. She has no complaints except for occasional headaches, which occur sometimes at work but never on weekends.

Jennifer has worked as a lab technician at a local polymer manufacturer for the past 6 years. She is concerned about possible chemical exposure at work. For protective equipment she uses eye protection, an apron, and latex gloves. There is no ventilation hood in the lab. The primary chemical she works with is N-methylpyrrolidone (NMP), a chemical used to dissolve a wide range of other chemicals. She is exposed to NMP on a weekly, and often daily, basis.

Jennifer’s exam is normal. The pregnancy test that you order is negative. You pull up the material safety data sheet (MSDS) for NMP online, which you review with Jennifer. The MSDS mentions no adverse reproductive effects, and Jennifer is relieved. However, knowing that MSDS entries are often incomplete and inaccurate with regard to information on the reproductive effects of the chemical, you investigate NMP in more detail on the Internet. You learn that in 2001, NMP was listed as a known reproductive toxicant in the state of California on the basis of animal studies.6 You search the developmental and reproductive toxicology database at the TOXNET Web site and find several entries, including a case of a pregnancy loss in a lab technician exposed to NMP.

On the basis of the information from the Internet and the toxicology database, you refer Jennifer to an occupational health specialist. You receive a note from the specialist after Jennifer’s consultation. She has recommended the use of additional safety precautions at Jennifer’s workplace, including a ventilator hood, a well-fitted respirator, neoprene rather than latex gloves (the former are more resistant), and continued use of the apron and eye protection.

The occupational health specialist asks you to explore with Jennifer the options for transferring out of the lab to a less toxic work environment, bearing in mind her legal rights and the potential for job loss or discrimination. You write a letter to Jennifer’s employer identifying NMP as a potential reproductive toxicant, highlighting the importance of avoiding reproductive toxicants, and the need to transfer Jennifer to a job without such exposure while she is trying to get pregnant and during pregnancy.

The employer transfers Jennifer to a position with less toxic exposure and invests in additional safety equipment for Jennifer and other employees. Had no other jobs been available, Jennifer might have decided to continue in the same job with improved protection. After the transfer, Jennifer’s headaches resolve.

This case illustrates that exposures to reproductive toxicants can occur at the workplace. With understanding and appropriate information, health care providers can advocate for their patients and make specific workplace recommendations that reduce the risk of exposure to reproductive toxicants.

*Case study adapted from GENERATIONS AT RISK: REPRODUCTIVE HEALTH AND THE ENVIRONMENT, published by The MIT Press.7

Medically Related Exposures:

Choose one (1):

Case A:  Jan was a nurse at the Lydecker Hospital in Minneapolis, MN.  She worked the night shift in the communicable diseases ward.

One evening a 28 year old male (Jason) was brought to the ward in a confused condition.  His chart indicated that he had AIDS and hepatitis C and was presently recovering from acute alcohol poisoning.

Toward the end of her shift Jan was doing patient assessment.  Upon entering Jason’s room Jan approached the bed to determine Jason’s vitals (blood pressure, temperature, etc.).  Upon waking Jason became extremely agitated, verbally and then physically abusive.  Jan, in an attempt to calm the patient, gently put her hand on his shoulder, which he then grabbed and proceeded to bite Jan several times, drawing blood and requiring 36 stitches.

Case B:  Jacob works as an infectious disease analyst at a local hospital.  While he is a physician, his job is largely administrative in that he analyzes data on suspected nosocomial (hospital induced) infections.  He notes that beginning the third week in March that three patients developed pneumonia after being in the hospital between 5-7 days.  Both were immunologically compromised.  Two patients developed surgical site infections.  During the fourth week in March he noted that two nurses had come down with pneumonia and one had come down with a skin condition.  Suspecting MRSA (Methicillin Resistant Staphylococcus Aureus) a full evaluation of hospital protocol was initiated.  It was found that the all patients to have come down with MRSA related illnesses been interviewed by the same intake personnel.  All nurses who had become ill had attended the ill patients.  It was later determined that the intake person was a carrier of MRSA.

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MN580 Discussion Board: Environmental Health in Pediatrics- Lead poisoning

July 2, 2025/in Nursing Questions /by Besttutor

 Topic: Assessment of Environmental Health, and Complementary Therapies in Pediatrics  (I chose Lead poisoning)

 

This week, there will be a variety of conditions assigned to you by your instructor pertaining to environmental health conditions. You are expected to present your initial topic including, but not limited to, the following items:

 

Use the below headings while answering the questions.

  • Pathophysiology
  • Epidemiology
  • Physical exam findings
  • Differential diagnoses and rationale
  • Management plan to include diagnostic testing, medications if applicable, follow-up plans and referrals if needed

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Nursing homework help

July 2, 2025/in Nursing Questions /by Besttutor

comment1

Understanding the health care system at the local level is important when planning an EBP implementation because the health care systems may differ depending on the location. One must take into account the demographics, such as region, population, access to resources, etc. One must also take into account the socioeconomic status of the population being treated. For example, some places may have more access to resources to other places, such as urban areas compared to rural areas. In regards to population one must take into account the age groups, their ethnicity, culture and spiritual beliefs, and values. All of those factors play a significant role in determining if the EBP implementation is effective or not.

comment2

Health care systems in various countries have different accountabilities. One cannot just bring change by implementing any Evidence-Based Research Project directly without having understood the implications of the health care system. It is imperative to carry thorough studies to gain knowledge about the extent to which health care systems have developed and what level of changes and advancements that are needed in this regard. For proper implementation of evidence-based practice, it is essential to examine care related to individuals and how the local staff is performing from monetary and technological resources provided to the organization (Stokke, 2017). The flow of information at the hospital also has to be analyzed depending upon which are a more considerable part of the practical implementation. The medical caretakers have the heavy responsibility of implementing and devising strategies to eliminate healthcare-associated risks, answer the clinical inquiries and work on them if they are needed for the betterment of the healthcare system. One should focus on giving knowledge on the importance of EBP to the whole staff and make them aware of evidence-based practices. All individuals including medical attendants should be taught to take an essential role in the implementation.

comment3

The two most essential change theories, in my opinion, are Lewin’s model and Social Learning theory. Lewin’s model has remained very useful in explaining the role of power in advancement or no advancement and implication of change. Change can only take place if the joined quality of one constraint becomes noteworthy than the consolidated quality of the restricting arrangement of powers. The social cognitive theory which was initially known as social learning theory considers that the change in behavior has been primarily impacted by individual variables and some properties of behavior. In comparison to both models, Lewin is more valid and reasonable. It disregards all components related to individuals that affect change. In contrast to this, the social cognitive theory is more influenced by what flows are drawn naturally and focuses on individual components. Lewin model is also more preferred because it takes into consideration, the outer and inner ecological conditions (Moses, 2015).

comment4

The two most commonly recognized change theories are Lewin’s and  Lippitt’s change models. The two are both very similar to one another in that they both look to evaluate when change in needed, initiated, and ultimately evaluated. The differences with each  are  how the creator ultimately expands further with these three stages.

Lewin’s Model consists of three stages: unfreezing, moving, and refreezing. The unfreezing stage ultimately looks at status quo, and increase driving forces for change; moving stage is the action stage in which the changes are implemented and involve people; and the final stage refreezing establishes the change as the new way of doing things with the reward of desired outcomes (Mitchell, 2013). Though Lewin’s model is simple and straight forward, as we all know now, change does not just happen as simple,  st raight  to the point stages. This is where Lippitt’s change model may work better not only for changes but changes to be done within the nursing field.

Lippitt’s model directly reflects change in a way  nurses  already know how. This is true because the language used to establish the model mimics that of the nursing process (Mitchell, 2013). Lippitt’s model is broken down into 7 phases, as follows: diagnose the problem (phase 1), a ssess motivation and capacity for  change ( phase 2), assess change agent’s motivation and resources (phase 3), select progressive change objective (phase 4), choose appropriate role of the change agent (phase 5), maintain change (phase 6), and terminate the helping relationship (phase 7) (Mitchell, 2013). Use of Lippitt’s model though it may not be as direct can help create a  clearer  and outlined  way of implementing change within the health care system. This is primarily why I would more likely use Lippitt’s model because  it  acknowledges more specific areas where change can either be a halted because oversight.

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Cultural considerations

July 2, 2025/in Nursing Questions /by Besttutor

Using the patient information provided respond to the following questions . What cultural considerations are important for you to remember while you interviewed Ms . Li. What is the abuse assessment screen? If abuse is discovered what should you do?

Pt I information

Pt: Sue Li

Age: 20

Ethnicity: Asian American

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Advanced Pathophysiology

July 2, 2025/in Nursing Questions /by Besttutor

Assignment: Adaptive Response

As an advanced practice nurse, you will examine patients presenting with a variety of disorders. You must, therefore, understand how the body normally functions so that you can identify when it is reacting to changes. Often, when changes occur in body systems, the body reacts with compensatory mechanisms. These compensatory mechanisms, such as adaptive responses, might be signs and symptoms of alterations or underlying disorders. In the clinical setting, you use these responses, along with other patient factors, to lead you to a diagnosis.

Consider the following scenarios:

Scenario 1:

Jennifer is a 2-year-old female who presents with her mother. Mom is concerned because Jennifer has been “running a temperature” for the last 3 days. Mom says that Jennifer is usually healthy and has no significant medical history. She was in her usual state of good health until 3 days ago when she started to get fussy, would not eat her breakfast, and would not sit still for her favorite television cartoon. Since then she has had a fever off and on, anywhere between 101oF and today’s high of 103.2oF. Mom has been giving her ibuprofen, but when the fever went up to 103.2oF today, she felt that she should come in for evaluation. A physical examination reveals a height and weight appropriate 2-year-old female who appears acutely unwell.  Her skin is hot and dry. The tympanic membranes are slightly reddened on the periphery, but otherwise normal in appearance. The throat is erythematous with 4+ tonsils and diffuse exudates. Anterior cervical nodes are readily palpable and clearly tender to touch on the left side. The child indicates that her throat hurts “a lot” and it is painful to swallow. Vital signs reveal a temperature of 102.8oF, a pulse of 128 beats per minute, and a respiratory rate of 24 beats per minute.

Scenario 2:

Jack is a 27-year-old male who presents with redness and irritation of his hands. He reports that he has never had a problem like this before, but about 2 weeks ago he noticed that both his hands seemed to be really red and flaky. He denies any discomfort, stating that sometimes they feel “a little bit hot,” but otherwise they feel fine. He does not understand why they are so red. His wife told him that he might have an allergy and he should get some steroid cream. Jack has no known allergies and no significant medical history except for recurrent ear infections as a child. He denies any traumatic injury or known exposure to irritants. He is a maintenance engineer in a newspaper building and admits that he often works with abrasive solvents and chemicals. Normally he wears protective gloves, but lately they seem to be in short supply so sometimes he does not use them. He has exposed his hands to some of these cleaning fluids, but says that it never hurt and he always washed his hands when he was finished.

Scenario 3:

Martha is a 65-year-old woman who recently retired from her job as an administrative assistant at a local hospital. Her medical history is significant for hypertension, which has been controlled for years with hydrochlorothiazide. She reports that lately she is having a lot of trouble sleeping, she occasionally feels like she has a “racing heartbeat,” and she is losing her appetite. She emphasizes that she is not hungry like she used to be. The only significant change that has occurred lately in her life is that her 87-year-old mother moved into her home a few years ago. Mom had always been healthy, but she fell down a flight of stairs and broke her hip. Her recovery was a difficult one, as she has lost a lot of mobility and independence and needs to rely on her daughter for assistance with activities of daily living. Martha says it is not the retirement she dreamed about, but she is an only child and is happy to care for her mother. Mom wakes up early in the morning, likes to bathe every day, and has always eaten 5 small meals daily. Martha has to put a lot of time into caring for her mother, so it is almost a “blessing” that Martha is sleeping and eating less. She is worried about her own health though and wants to know why, at her age, she suddenly needs less sleep.

To Prepare

  • Review the three scenarios, as well as Chapter 6 in the Huether and McCance text.
  • Identify the  pathophysiology of the disorders presented in each of the three scenarios, including their  associated alterations. Consider the adaptive responses to the alterations.
  • Review the examples of  “Mind Maps—Dementia, Endocarditis, and Gastro-oesophageal Reflux Disease  (GERD)” media in this week’s Learning Resources. Then select one of the disorders you identified  from the scenarios. Use the examples in the media as a guide to construct a  mind map for the disorder you selected. Consider the epidemiology, pathophysiology,  risk factors, clinical presentation, and diagnosis of the disorder, as well as  any adaptive responses to alterations.

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Analyze a Current Health Care Problem or Issue

July 2, 2025/in Nursing Questions /by Besttutor

 Write a 4-6 page analysis of a current problem or issue in health care, including a proposed solution and possible ethical implications.

TOPIC: Medication Errors

 

  1. Describe the health care problem or issue you selected. Medication errors.
  2. Identify possible causes for the problem or issue.
  3. Use scholarly information to explain the health care problem or issue.
    • Identify at least three scholarly or academic peer-reviewed journal articles about the topic.
      • You may use articles you found while working on Assessment 2 or you may search an online library for scholarly articles.
      • You may find the applicable Undergraduate Library Research Guide helpful in your search.
    • Assess the credibility of the information sources.
    • Assess the relevance of the information sources.
  4. Analyze the problem or issue.
    • Describe the setting or context for the problems or issues.
    • Describe why the problem or issue is important to you.
    • Identify groups of people affected by the problem or issue.
  5. Discuss potential solutions for the problem or issue.
    • Compare your opinion with other opinions you find in sources from the Capella Library.
    • Provide the pros and cons for one of the solutions you are proposing.
  6. Analyze the ethical implications if the potential solution (the one for which you provide pros and cons) were to be implemented.
    • Discuss the pros and cons of implementing the proposed solution from an ethical principle point of view.
    • Provide examples from the literature to support the points you are making.
  7. Describe what would be necessary to implement the proposed solution.

Attached is an example paper of a proficient rating for this assignment.

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Comment

July 2, 2025/in Nursing Questions /by Besttutor

Discussion #1

 

There are many different risk factors associated with myocardial infarction (MI) or heart attack. Risk factors that are uncontrollable are age, gender and heredity (American Heart Association, 2018). Risk factors that are modifiable are smoking, high cholesterol, blood pressure, obesity and sedentary lifestyle (American Heart Association, 2018). Other risk factors are diabetes, alcohol and stress (American Heart Association, 2018). Although many of these risk factors are preventable, approximately 370,000 people in the US experience an MI annually (Samoraphop, Zahrli, & Hisako, 2018).        Mr. Smith’s injury was a result of hypoxia. Hypoxia develops when there is a lack of oxygen (McCance & Heuther, 2014). A common type of hypoxia is ischemia, which is usually caused by a narrowing or blockage of arteries (McCance & Heuther, 2014). The effects of myocardial ischemia become irreversible and causes necrosis after about twenty minutes (McCance & Heuther, 2014). The most common type of myocardial ischemia is caused by arteriosclerosis which is a gradual narrowing of the arteries induced by plaque build-up (McCance & Heuther, 2014). Mr. Smith’s angiography and requirement of the usage of IV clot dissolvent supports this analysis.         Reversible cell injury is capable when oxygen is supplied back to the cell within a certain amount of time. Irreversible is when the cell has structural changes, mainly damage to the nucleus and has become necrotic (McCance & Heuther, 2014). Rather a cell’s injury is reversible or irreversible depends on factors such as length of time the damage has taken place and the type of damage. Cells can also adapt to damage and still remain functioning (McCance & Heuther, 2014).         The pathophysiological changes that occur to the heart during an MI can be detrimental, it is important to ensure quick diagnostic confirmation of an acute MI to prevent further complication and death. Within 1 minute the heart becomes pale and is not able to contract as efficiently (McCance & Heuther, 2014). In 3-5 minutes. the section of the affected heart stops contracting this causes mitochondria oxygenation to decrease which decreases the production of ATP (McCance & Heuther, 2014). Cellular swelling begins along with the loss of integrity to the plasma membrane (McCance & Heuther, 2014). With the integrity of the plasma membrane compromised the sodium-potassium pump and the sodium-calcium exchanges fail resulting in cellular death if oxygen supplies are not returned (McCance & Heuther, 2014).         Subjective findings for MI are patient complaints of shortness of breath. Chest pain can be described as having severe pain or as though a lot of pressure is “sitting” on the chest (McCance & Heuther, 2014). Some patients complain of nausea and vomiting along with pain described as “shooting” in jaw or left arm (McCance & Heuther, 2014). Objective data for diagnosis of an MI are EKG findings and cardiac enzyme results (McCance & Heuther, 2014).

 

 

Discussion #2

 

Coronary heart disease (CHD) is one of the leading causes of death and accounts for nearly 25% of all deaths in America (McCance & Huether, 2014, p. 171).  Myocardial infarction (MI) results from decreased blood supply to the heart that causes damage to heart tissue from an inadequate supply of oxygen (McCance & Huether, 2014, p. 171).  There are two types of risk factors associated with CHD and MI: non-modifiable and modifiable.  Conventional or non-modifiable risk factors consist of demographics such as age, gender, and family history (McCance & Huether, 2014, p. 1149).  The modifiable risk factors associated with CHD include conditions such as dyslipidemia, hypertension, diabetes and insulin resistance and lifestyle factors such as smoking, obesity, diet, and activity level (McCance & Huether, 2014, p. 1149).

In the provided case study, Mr Smith has sustained ischemic cell injury.  Ischemic cell injury is categorized by lack of oxygen, through reduced blood supply, that causes the destruction of the cell structure and the cell membrane (McCance & Huether, 2014, p. 55).  The lack of adequate oxygen is called hypoxia, the most common cause of ischemia, and is the number one cause of cellular injury (McCance & Huether, 2014, p. 56).  Hypoxia results from a reduction in oxygen that can be related to a number of conditions including anemia, respiratory disorders, and cardiovascular diseases (McCance & Huether, 2014, p. 56).

Cell injury can be either reversible with the possibility of recovery or non-reversible that results in cell death.  Reversible cell injury responses include loss of adenosine triphosphate (ATP), cellular swelling, ribosomal detachment, and autophagy of the lysosomes (McCance & Huether, 2014, p. 55).  Irreversible cell injury is called the “point of no return” and is considered a biochemical puzzle due to the exact mechanism of action responsible for the cell’s transition from reversible to non-reversible remaining undecided (McCance & Huether, 2014, p. 55).  Factors exist, such as nutritional status, that play a role in the cell’s ability to recover and to the extent of damage that occurs from the injury (McCance & Huether, 2014, p. 55).

The pathophysiological changes that occur during an MI began less than one minute after reduction of myocardial blood supply (McCance & Huether, 2014, p. 58).  Cardiac cells are able to survive ischemic conditions for approximately 20 minutes prior to cell death however ECG changes are visible as early as 30-60 seconds after hypoxia occurs (McCance & Huether, 2014, p. 1160).  Immediately after reduced blood flow the affected myocardial tissue becomes cyanotic and all oxygen reserves are used rapidly leading to the use of anaerobic metabolism (McCance & Huether, 2014, p. 1159).  The use of glycogen as an energy source is inadequate to meet the total energy requirements of the myocardium resulting in acidosis from electrolyte imbalances (McCance & Huether, 2014, p. 1159).  These imbalances make the myocardial tissue vulnerable to the effects of lysosomal enzymes, which further reduces the contractile function and impulse conduction and leads to heart failure (McCance & Huether, 2014, p. 1159).

As ischemic damage occurs, the first symptom is typically acute, sudden onset of severe chest pain that has been described as heavy and crushing, like there is “an elephant on my chest”, with radiation reported to the jaw, neck, back, shoulder, and left arm (McCance & Huether, 2014, p. 1160).  Some reports of atypical presentation of MI, usually associated with the elderly or those with diabetes, include no pain, nausea and vomiting, or uncontrollable indigestion (McCance & Huether, 2014, p. 1160).  Objective changes that can be observed include a temporary increase in heart rate (HR) and blood pressure (BP) as the body attempt to compensate, abnormal extra heart sounds resulting from left ventricular dysfunction, cardiac murmurs related to valvular insufficiency, respiratory congestion including percussion that is dulled and inspiratory crackles at the lung bases, and skin that is cool and clammy as the result of peripheral vasoconstriction (McCance & Huether, 2014, p. 1160).

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