100 words positive post by tonight at 9

 

From my experience and observation as a mental health nurse, I remember a 20-year-old male patient who was admitted to my facility with a diagnosis of schizophrenia, self-harming behaviors, and substance abuse. This patient had a long history of using fentanyl, methamphetamine, and street drugs like Mexican Percocet’s. He has been admitted numerous times to our facility for substance abuse detox. This patient had been on several dosages of Clozapine which was prescribed by the provider to help with his acute case of mental illness. A week after starting his initial Clozapine medication, this patient was complaining of discomfort, chest pain and will explain to the staff that his pain was getting worse daily. The physician ordered EKG to check the activity of his heart.

Pharmacodynamics

Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Clozapine also binds to D1, D3, and D5 receptors, and has a high affinity for the D4 receptor (McEvoy, 2018). Researchers shows that it includes the limbic system.

Pharmacokinetics

              Clozapine is absorbed quickly, first-pass metabolism reduces its bioavailability to 60 to 70 percent of the administered dose; food has little effect on the bioavailability of clozapine (Patuszynski & Applegate, 2017). The eliminated half-life of clozapine averages a period of 14 hours under certain conditions, but there is considerable variability across individuals. For example, it depends on each individual own metabolism and its underlying factors (McEvoy, 2018).

Care plan

Because clozapine has an increased incidence of clozapine-induced myocarditis as well as cardiomyopathy. Patients who are currently taking clozapine will need to be monitored closely by a cardiologist. Staff must educate the patient regarding the risk that are involved with this medication. “We need to understand that there should be standardized and mandatory plans of care which should include troponin levels as well as EKGs and echocardiograms at various times during inpatient stays” (Kir et al., 2020).  “Other factors to consider would be airway clearance due to excessive salvation and neutropenia” (Okada et al., 2020). Careful patient monitoring is essential when taking clozapine therapy. It is important to educate patient to keep to their lab appointments where they could monitor blood levels.

References

 Kır, Y., Baskak, B., Kuşman, A., Sayar-Akaslan, D., Özdemir, F., Sedes-Baskak, N., Süzen, H.

S., & Baran, Z. (2020). The relationship between plasma levels of clozapine and N-desmethyclozapine as well as M1 receptor polymorphism with cognitive functioning and associated cortical activity in schizophrenia. Psychiatry Research: Neuroimaging303

Okada, T., Kumakura, J., Yasuda, M., & Suda, S. (2020). Treatment-resistant schizophrenia

successfully maintained with brexpiprazole following abrupt withdrawal of clozapine due to neutropenia. Asian Journal of Psychiatry47

Patuszynski, D., & Applegate, P. M. (2017). Suspected Clozapine-Induced Cardiomyopathy and

Heart Failure With Reduced Ejection Fraction. Federal practitioner: for the health care professionals of the VA, DoD, and PHS34(4), 20–22.

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100 word positive post with three refences due today at 10 pm

 

Main Post

Pharmacokinetics and Pharmacodynamics

As advanced practice nurses it is important that we understand pharmacokinetics and pharmacodynamics when caring for our patients. There are many factors to consider when prescribing medications because not one person is the same. Pharmacokinetics is the study of drug movement throughout the body, and has four basic processes: absorption, distribution, metabolism, and excretion (Rosenthal, 2021, p 13). Pharmacodynamics is the study of the biochemical and physiologic effects of drugs on the body and the molecular mechanisms by which those effects are produced (Rosenthal, 2021, p 22). In my experience I can not pinpoint one specific scenario in which pharmacokinetic and pharmacodynamic factors altered an anticipated response to a drug but multiple scenarios.

I can think of things to consider when prescribing medications like their medical history, medications they take, whether prescribed or over the counter, compliance, genetics, age, race, and family history. Other things to consider is the patients liver function and renal function, which affect the drugs absorption and excretion rate. One class of drugs that comes to mind are chemotherapy medications. Not everyone has the same outcome with chemotherapeutic agents when treating cancers. Another class of medications are psychotropic medications, some psych medications work better for others and do not work at all for some. And one of the most common ailments hypertension, antihypertensive drugs that work for some and not others. Immunosuppressed, CHF, renal failure, liver failure patients and patients with multiple ailments on multiple medications, all have to be prescribed medications carefully because of possible polypharmacy and drug interactions. A-fib patients prescribed coumadin needing their PT/INR checked to make sure their coumadin is therapeutic, educating them not to eat green leafy vegetables or drink grapefruit juice.

A patient’s genetics may play a role in whether the medication prescribed is going to work or not. It became evident in the 60’s that therapeutic doses of psychotropic medications vary markedly from person to person, with some patients failing to respond despite treatment with high dosages (Lerer, 2004, p158). Among many factors that may influence the drug response, hepatic function, and drug metabolism ae of great importance for nearly all medications used in psychiatry and even more importantly patient compliance with medication use (Lerer, 2004, p158). The CYP2D6 genetic polymorphism was discovered in late 1970’s and represents one of the most intensively studied monogenic variations in drug metabolism, approx. 7% of Caucasians are poor metabolizers of CYP2D6 substrates while the rest are considered as extensive metabolizers (Lerer, 2004, p160). CYP2D6 enzyme has particular significance for clinical psychiatry as it is involved in clearance of many psychotropic drugs such as tricyclic, antidepressants, selective serotonin reuptake inhibitors, classical antipsychotics, some atypical antipsychotics, drugs of abuse and codeine (Lerer, 2004, p160). In patients who rapid metabolize and have multiple copies of CYP2D6, conventional dose titration may cause delays in therapeutic response and lead to prolonged inpatient hospitalization. It is important to know our patient’s, do lab work according to the drugs being prescribed and refer our patients to specialty physicians if necessary.

                Another consideration is gender when prescribing medications. Research shows that women have different absorption due to lower gastric pH and longer gastrointestinal transit, lower P-glycoprotein expression, different body fat percentage than men, and that estrogen in women can affect drug metabolizing enzymes (Pierzchlinska, 2018, p 117). All of the topics discussed are why it is so important to develop an individualized care plan for each patient to provide the best care possible. The care plan should include goals of therapy, interventions, and follow up evaluation of treatment outcomes. Well rounded individualized treatment plans specific for each patient allow patients to establish trusting relationships with their providers.

Reference

Lerer, B. (2004). Pharmacogenetics of psychotropic drugs. (electronic source). Cambridge University Press.

Pierzchlinska, A., & Bialecka, M. (2018). An introduction to gender differences in neurological treatment. Aktualnosci Neurologiczne, 18(3), 117-122. https://doi-org.ezp.waldenulibrary.org/10.15557/AN.2018.0016

Rosenthal, L.D., & Burchum, J.R. (2021). Lehne’s pharmacotherapeutics for advanced practice nurses and physician assistants (2nd ed.) St. Louis, MO: Elsevier

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Community DQ 15.

Read chapters 25 of the class textbook and review the PowerPoint presentations located in the PowerPoint folder. Once done answer the following questions.   

1. Mention and discuss the role of nursing in occupational health

2. Describe and discuss the four types of exposures and hazards in the work place

APA style (intext citations and references)

Plagiarism FREE

 A minimum of 3 evidence-based references no older than 5 years must be used 

800 words

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Working With Children and Adolescents Versus Adults

 PLEASE FOLLOW THE INSTRUCTIONS BELOW

4 REFERENCES

ZERO PLAGIARISM

Infant, childhood, and adolescent development are a continual interplay between nature (genetic or biologic predisposition) and nurture (environmental experiences). The nature/nurture continuum and debate will always be a part of your career as a PMHNP.  Knowing common developmental milestone is important in the role as a child provider. Not only is it essential to the diagnostic process, but it is also important to the interdisciplinary interactions with other mental health professionals. The study of normal developmental processes, however, is only one tool that allows the mental health professional to understand the child being evaluated. There are many different assessment instruments and interviewing techniques that PMHNPs can have in their toolkit when working with children and adolescents.

In this Discussion, you examine the differences in assessing and treating children and adolescents versus adults. You take into consideration your own clinical experiences, as well as your experiences in your clinical rotation, and the information from the readings thus far.

Learning Objectives

Students will:
  • Analyze the importance of developmental assessments
  • Analyze assessment instruments used for evaluating children and adolescents
  • Analyze treatment options used for children and adolescents
  • Analyze roles parents play in assessment and treatment

To Prepare for the Discussion

  • Review the Learning Resources concerning psychiatric assessments and assessment tools.

Note: For this Discussion, you are required to complete your initial post before you will be able to view and respond to your colleagues’ postings. Begin by clicking on the “Post to Discussion Question” link and then select “Create Thread” to complete your initial post. Remember, once you click submit, you cannot delete or edit your own posts and cannot post anonymously. Please check your post carefully before clicking Submit!

By Day 3

Post your answers to the following:

  • Explain why a developmental assessment of children and adolescents is important.
  • Describe two assessment instruments and explain why they are used for children and adolescents but not adults. 
  • Describe two treatment options for children and adolescents that may not be used when treating adults.
  • Explain the role parents play in assessment and treatment.

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Community, complementary and crisis reflection (Due 24 Hours)

 

1) Minimum 9 full pages (Follow the 3 x 3 rule: minimum three paragraphs per part)  Can  write in the first person 

              Part 1: Minimum 3 pages

              Part 2: minimum 3 pages

              Part 3: minimum 3 pages

Submit 1 document per part

2)¨******APA norms

          All paragraphs must be narrative and cited in the text- each paragraphs

          Bulleted responses are not accepted

          Can write in the first person 

          Dont copy and pase the questions.

          Answer the question objectively, do not make introductions to your answers, answer it when you start the paragraph

     

    Submit 1 document per part

3)****************************** It will be verified by Turnitin (Identify the percentage of exact match of writing with any other resource on the internet and academic sources, including universities and data banks) 

********************************It will be verified by SafeAssign (Identify the percentage of similarity of writing with any other resource on the internet and academic sources, including universities and data banks)

4) Minimum 4 references per part not older than 5 years

5) Identify your answer with the numbers, according to the question. Start your answer on the same line, not the next

Example:

Q 1. Nursing is XXXXX

Q 2. Health is XXXX

6) You must name the files according to the part you are answering: 

Example:

Part 1.doc 

Part 2.doc 

__________________________________________________________________________________

Part 1: Community nursing (Reflection)

Purpose :

The purpose of this assignment is to provide the student an opportunity to reflect on selected RN-BSN competencies acquired through the course.  

 

Organization:

a. Introduction

b. Course Reflection 

c. Conclusion

Include (Mendatory):

  

1. “Demonstrate basic knowledge of healthcare policy, finance, and regulatory environments, including local, state, national, and global healthcare trends.

2. Describe how health care is organized and financed, including the implications of business principles, such as patient and system cost factors.

3. Compare the benefits and limitations of the major forms of reimbursement on the delivery of healthcare services.

4. Examine legislative and regulatory processes relevant to the provision of health care.

5.  Cultural Competence: Awareness, Sensitivity, and Respect  

6.   Care Management, Case Management, and Home Healthcare 

7.  Community Preparedness: Disaster and Terrorism 

 

Part 2: Complementary and alternativge health care (Course reflection)

Pupose:

 The purpose of this assignment is to provide the student an opportunity to reflect on selected RN-BSN competencies acquired through the course.  

 Organization:

a. Introduction

b. Course Reflection 

c. Conclusion

Include (mandatory):

1.  Apply concepts of quality and safety using structure, process, and outcome measures to identify clinical questions and describe the process of changing current practice.

2. Promote factors that create a culture of safety and caring. 

3. Promote achievement of safe and quality outcomes of care for diverse populations. 

4. Apply quality improvement processes to effectively implement patient safety initiatives and  monitor performance measures, including nurse-sensitive indicators in the microsystem of care.  

5.  Define complementary and alternative practices as identified by current health paradigms. 

6. Discuss history for complementary and alternative medicine. 

7. Given case studies, describe the extent to which complementary and alternative health practices are encouraged and used among multiple cultures.   

Part 3: Crisis intervention (Course reflection)

Pupose:

 The purpose of this assignment is to provide the student an opportunity to reflect on selected RN-BSN competencies acquired through the course.  

 Organization:

a. Introduction

b. Course Reflection 

c. Conclusion

Include (mandatory):

  

1. “Integrate theories and concepts from liberal education into nursing practice.

2. Synthesize theories and concepts from liberal education to build an understanding of the human experience. 

3. Use skills of inquiry, analysis, and information literacy to address practice issues.

4. Use written, verbal, non­verbal, and emerging technology methods to communicate effectively.

5.  Crisis of Lethality 

6.  The Intervention and Assessment Models  

7.  Telephone and Online Crisis Counseling 

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LITERATURE

 How effectively do you think the Coyne et al. study and the Messina et al. study both used their review of literature to help the reader understand why the research question was asked? How could they have done it more effectively? please include in-text citation and references.

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Ethical, aging and health care policy (Due 24 hours)

 

1) Minimum 9 full pages (Follow the 3 x 3 rule: minimum three paragraphs per part)

 

Parts 3, 4 and 5 must be different. Different writing and perspective, but always answering questions objectively

              Part 1: Minimum 3 pages

              Part 2: minimum 3 pages

              Part 3: minimum 1 page

              Part 4: Minimum 1 page

              Part 5: minimum 1 page

Submit 1 document per part

2)¨******APA norms

          All paragraphs must be narrative and cited in the text- each paragraphs

          Bulleted responses are not accepted

          Dont write in the first person 

          Dont copy and pase the questions.

          Answer the question objectively, do not make introductions to your answers, answer it when you start the paragraph

    Submit 1 document per part

3)****************************** It will be verified by Turnitin (Identify the percentage of exact match of writing with any other resource on the internet and academic sources, including universities and data banks) 

********************************It will be verified by SafeAssign (Identify the percentage of similarity of writing with any other resource on the internet and academic sources, including universities and data banks)

4) Minimum 3 references per part not older than 5 years

   Part 1 and 2: Minimum 4 references not older than 5 years

5) Identify your answer with the numbers, according to the question. Start your answer on the same line, not the next

Example:

Q 1. Nursing is XXXXX

Q 2. Health is XXXX

6) You must name the files according to the part you are answering: 

Example:

Part 1.doc 

Part 2.doc 

__________________________________________________________________________________

Part 1: Ethical and Nursing (Course reflection)

Purpose :

  

The purpose of this assignment is to provide the student an opportunity to reflect on selected RN-BSN competencies acquired through the course.  

Organization:

a. Introduction

b. Course Reflection 

c. Conclusion

Include (Mendatory):

  

1. Identify the different legal and ethical aspects in the nursing practice (ACCN Essential V; QSEN: patient-centered care, teamwork and collaboration).

2. Analyze the legal impact of the different ethical decisions in the nursing practice (ACCN Essential V; QSEN: patient- centered care, teamwork and collaboration).

3. Understand the essential of the nursing law and ethics (ACCN Essential V; QSEN: patient-centered care, teamwork and collaboration).

4. Promote the image of nursing by modeling the values and articulating the knowledge, skills, and attitudes of the nursing profession.

5. Demonstrate professionalism, including attention to appearance, demeanor, respect for self and others, and attention to professional boundaries with patients and families as well as among caregivers.

6. Demonstrate an appreciation of the history of and contemporary issues in nursing and their impact on current nursing practice.

7. Reflect on one’s own beliefs and values as they relate to professional practice.

8. Identify personal, professional, and environmental risks that impact personal and professional choices, and behaviors 

Part 2: Nursing and aging (Course reflection)

Purpose :

  

The purpose of this assignment is to provide the student an opportunity to reflect on selected RN-BSN competencies acquired through the course.  

Organization:

a. Introduction

b. Course Reflection 

c. Conclusion

Include (Mendatory):

1. The students will identify the physiological process of aging. 

2. The students will be able to differentiate the adaptative human response to the aging process. 

3. The student will be able to manage and care older adults and their families.  

4.. Implement holistic, patient centered care that reflects an understanding of human growth and development, pathophysiology, pharmacology, medical management, and nursing management across the health illness continuum, across the lifespan, and in all healthcare settings. 

5. Communicate effectively with all members of the healthcare team, including the patient and the patient’s support network. 

6. Deliver compassionate, patient centered, evidence-based care that respects patient and family preferences.  

Parts 3, 4 and 5 must be different. Different writing and perspective, but always answering questions objectively

Part 3: Health care policy 1

1. Examine how might nurses and nursing organizations improve policies to encourage the judicious use of antibiotics in humans? 

2. Identify the correlation between global disease surveillance and domestic disease surveillance, and the significant role the family nurse practitioner plays. 

Part 4: Health care policy 2

1. Examine how might nurses and nursing organizations improve policies to encourage the judicious use of antibiotics in humans? 

2. Identify the correlation between global disease surveillance and domestic disease surveillance, and the significant role the family nurse practitioner plays. 

Part 5: Health care policy 3

1. Examine how might nurses and nursing organizations improve policies to encourage the judicious use of antibiotics in humans? 

2. Identify the correlation between global disease surveillance and domestic disease surveillance, and the significant role the family nurse practitioner plays. 

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Policy Analysis Paper- Food and drug regulation (Due 48 hours)

 

1) Minimum 7 full pages (Follow the 3 x 3 rule: minimum three paragraphs per part)

              

2)¨******APA norms

          All paragraphs must be narrative and cited in the text- each paragraphs

          Bulleted responses are not accepted

          Dont write in the first person 

          Dont copy and pase the questions.

          Answer the question objectively, do not make introductions to your answers, answer it when you start the paragraph

3)****************************** It will be verified by Turnitin (Identify the percentage of exact match of writing with any other resource on the internet and academic sources, including universities and data banks) 

********************************It will be verified by SafeAssign (Identify the percentage of similarity of writing with any other resource on the internet and academic sources, including universities and data banks)

4) Minimum 6 references per part not older than 5 years (No blogs or web pages- Only official webs: FDA, CDC…)

5) Identify your answer with the numbers, according to the question. Start your answer on the same line, not the next

Example:

Q 1. Nursing is XXXXX

Q 2. Health is XXXX

__________________________________________________________________________________

Topic: Food and drug regulation

Purpose : 

To investigate & integrate knowledge of advanced nursing practice, scholarly inquiry, & leadership by examining a policy at the level of clinical practice, health care systems, or public/social health policy. 

 

You must strictly follow the following scheme. You must use titles and subtitles.

Introduction (Maximum 1 pages): 

1. Generally define & describe the policy issue to be addressed. 

2. Identify the purpose of analysis, the targeted level of policy (i.e., clinical practice, health care systems, or public/social health) & significance of topic.

3. Identify questions the policy analysis is intended to address.  

Background:

1. Provide details of the issue or problem, including its nature/scope,

relevant literature & history, & the context within which the issue

exists.

2. Describe existing policy addressing the issue, if any.

3. Discuss strengths & shortcomings in existing policy.

4. Identify & describe key stakeholders (individuals & groups) that

are or will be affected by the policy & why

Analysis 

1. Identify alternative policies to achieve objectives. 

2. Establish/identify criteria that will be used for selection of “best” policy. 

3. Evaluate each alternative & its potential impact relative to the healthcare & patient outcomes. 

4. Assess the trade-offs between alternatives. 

Recommendations  

 1. Based on the analysis, identify the “best” alternative to address the current issue & policy situation. 

2. Provide rationale for selection. 

3. Describe possible strategies to implement selected alternative. 

4. Identify barriers to implementation of selected alternative. 

5. Describe methods to evaluate policy implementation.  

Discussion (1 page) 

1.  Discuss analysis & recommendations relative to the original questions identified, & the level of policy it is intended to address (i.e., clinical practice, health care systems, or public). 

2. Identify limitations of analysis. 

3. Discuss implications for practice, education, research, & policymaking.  

Conclusion ( minimum 1/2 page) 

1. Summarize findings & recommendations of analysis 

2. Identify questions to be addressed in future studies or policy analyses 

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Tomorrow 9 (Trends 1)

Discuss the correlation between nursing education and positive patient outcomes. Include current research that links patient safety outcomes to advanced degrees in nursing. Based on some real-life experiences, explain whether you agree or disagree with this research.

Wednesday 9

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Thursday 10 (Trends 2)

Discuss the difference between a DNP and a PhD in nursing. Discuss which of these you would choose to pursue if you decide to continue your education to the doctoral level and explain why.

Thusrday 10

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